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Search Results for " interleukin 22 "

Targets Recommended: Interleukin

4

抑制剂 & 化合物

22

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T76775	Fezakinumab ILV 094	Interleukin	Immunology/Inflammation
	Fezakinumab 是一种有效的白细胞介素 22 (IL-22) 单克隆抗体。Fezakinumab 可用于研究银屑病、类风湿性关节炎和特应性皮炎等免疫系统疾病和炎症相关疾病。
T1955	SB225002	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	SB225002 是一种有效的选择性 CXCR2 拮抗剂，抑制白介素 IL-8 与 CXCR2 的结合，IC50为 22 nM。
T76803	Elsilimomab
	Elsilimomab (B-E8) 是一种抗白介素-6 (IL-6) 的 IgG1单克隆抗体，其 KD 为 22 pM，IC50为 1.4 nM。Elsilimomab 可用于多发性骨髓瘤、肾细胞癌和类风湿性关节炎 (RA) 的研究。
T69451	R-130823
	R-130823 is a ighly selective inhibition against mitogen-activated protein kinase p38alpha (IC50=22 nM). The release of tumor necrosis factor-alpha, interleukin-1beta, -6 and -8 was inhibited in lipopolysaccharide-stimulated human blood pretreated by R-130823 , with IC50 values of 0.089, 0.066, 0.95 and 0.16 microM, respectively. R-130823 reduced the established hind paw swelling in rat adjuvant-induced arthritis, while methotrexate showed no suppression. In the same model, R-130823 ameliorated ...

化合物

Cat.No: T76775

Synonym: ILV 094

Target: Interleukin

Cat.No: T1955

Target: CXCR

Cat.No: T76803

Cat.No: T69451

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03490	IL-22 Protein, Human, Recombinant IL-TIF,白介素,IL-22,interleukin 22,I...	Human	E. coli
	IL-22 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.9 kDa and the accession number is A0A7R8C389.
TMPY-04286	IL-22RA1 Protein, Rat, Recombinant (hFc) interleukin 22 receptor, alpha 1,inter...	Rat	HEK293 Cells
	IL-22RA1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.8 kDa and the accession number is A0A8I6A0L8.
TMPY-04287	IL-22RA1 Protein, Rat, Recombinant (His) interleukin 22 receptor, alpha 1,inter...	Rat	HEK293 Cells
	IL-22RA1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.5 kDa and the accession number is A0A8I6A0L8.
TMPY-04087	IL-22RA1 Protein, Canine, Recombinant (His) interleukin 22 receptor, alpha 1,inter...	Canine	HEK293 Cells
	IL-22RA1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is A0A8C0M3C4.
TMPY-04002	IL-22RA1 Protein, Canine, Recombinant (hFc) interleukin 22 receptor, α1,interleuki...	Canine	HEK293 Cells
	IL-22RA1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.2 kDa and the accession number is A0A8C0M3C4.
TMPJ-01340	IL-22 Protein, Mouse, Recombinant (mFc) IL-10-related T-cell-derived-inducible factor,白介素,Interl...	Mouse	HEK293 Cells
	IL-22 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 50-65 KDa and the accession number is Q9JJY9.
TMPJ-00061	IL-22 Protein, Human, Recombinant (hIgG2 hFc) 白细胞介素,Cytokine Zcyto18,Interleukin-22,IL-T...	Human	HEK293 Cells
	IL-22 Protein, Human, Recombinant (hIgG2 hFc) is expressed in HEK293 mammalian cells with C-hIgG2 Fc tag. The predicted molecular weight is 50-62 KDa and the accession number is Q9GZX6.
TMPK-00661	IL-22 Protein, Cynomolgus, Recombinant (His) TIFIL-23,IL-22,IL-D110,IL-TIF,TIFa,Interleukin<...	Cynomolgus	HEK293 Cells
	The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production. IL-22 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 17.69 kDa and the accession number is G7PHZ7.
TMPJ-00062	IL-22 Protein, Human, Recombinant (hIgG4 hFc) IL-10-related T-cell-derived-inducible factor,Interleuki...	Human	HEK293 Cells
	IL-22 Protein, Human, Recombinant (hIgG4 hFc) is expressed in HEK293 mammalian cells with C-hIgG4 Fc tag. The predicted molecular weight is 50-75 KDa and the accession number is Q9GZX6.
TMPY-04973	IL-22 Protein, Human, Recombinant (His) TIFa,IL-22,TIFIL-23,白细胞介素,ILTIF,白介素,zcyto18,IL-TIF,...	Human	P. pastoris (Yeast)
	IL-22 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 18.1 kDa and the accession number is A0A7R8C389.
TMPJ-00119	IL-22RA2 Protein, Human, Recombinant (hFc) Cytokine Receptor Family 2 Member 10,CRF2-10,IL-22R...	Human	HEK293 Cells
	Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
TMPK-01194	IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated IL-22,Cytokine Zcyto18,白细胞介素,IL-TIF,白介素,Interle...	Mouse	E. coli
	The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production. IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 19.7 kDa and the accession number i...
TMPJ-01339	IL-22 Protein, Mouse, Recombinant (E. coli) IL-TIF Alpha,Il22a,IL-22,Iltifa,IL-TIF,IL-...	Mouse	E. coli
	IL-22 Protein, Mouse, Recombinant (E. coli) is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is Q9JJY9.
TMPY-01324	IL-22BP Protein, Human, Recombinant (His & hFc) interleukin 22 receptor, alpha 2,CRF2-S1,I...	Human	HEK293 Cells
	IL-22BP Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 52.8 kDa and the accession number is Q969J5-2.
TMPY-01220	IL-22BP Protein, Human, Recombinant (His) ZCYTOR16,CRF2X,IL-22R-α-2,interleukin ...	Human	HEK293 Cells
	IL-22BP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.1 kDa and the accession number is Q969J5-2.
TMPY-04900	IL-22BP Protein, Human, Recombinant (hFc) IL-22BP,CRF2X,ZCYTOR16,IL-22R-α-2,inte...	Human	HEK293 Cells
	IL-22BP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 55 kDa and the accession number is Q969J5-1.
TMPJ-00076	IL-28B Protein, Human, Recombinant IL-28C,IFN-λ-4,IFNL4,Interferon λ-4,IL28B,IL-28B,Interle...	Human	HEK293 Cells
	Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed...
TMPK-00512	IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His) IL18R1,IL-1 Rrp,CD218a,IL18Ra,IL-18Ra,IL-18 R alpha,IL1RRP,I...	Cynomolgus	HEK293 Cells
	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Pr...
TMPK-01071	IL-22RA1 Protein, Mouse, Recombinant (hFc) IL-22R α1,IL22R,zcytoR11,IL-TIF-R1,CRF2-9,...	Mouse	HEK293 Cells
	Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3. IL-22RA1 Pr...
TMPK-01105	IL-22RA1 Protein, Human, Recombinant (hFc) IL-22R-alpha-1,CRF2-9,IL-TIF-R1,IL-22R-α-1...	Human	HEK293 Cells
	Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3. IL-22RA1 Pr...
TMPJ-00194	IL-20RB Protein, Human, Recombinant (hFc) DIRS1,IL-20R-β,Interleukin-20 receptor subunit β,IL...	Human	HEK293 Cells
	Interleukin-20 receptor subunit beta（IL20RB） is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do no...
TMPK-00405	IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated IL-7R-alpha,IL-7R,ILRA,IL-7R-α,IL-17RA,CANDF5,IL17R,CDw217,C...	Human	HEK293 Cells
	Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22.

重组蛋白

IL-22 Protein, Human, Recombinant

Cat.No: TMPY-03490

Species: Human

Expression System: E. coli

IL-22RA1 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-04286

Species: Rat

Expression System: HEK293 Cells

IL-22RA1 Protein, Rat, Recombinant (His)

Cat.No: TMPY-04287

Species: Rat

Expression System: HEK293 Cells

IL-22RA1 Protein, Canine, Recombinant (His)

Cat.No: TMPY-04087

Species: Canine

Expression System: HEK293 Cells

IL-22RA1 Protein, Canine, Recombinant (hFc)

Cat.No: TMPY-04002

Species: Canine

Expression System: HEK293 Cells

IL-22 Protein, Mouse, Recombinant (mFc)

Cat.No: TMPJ-01340

Species: Mouse

Expression System: HEK293 Cells

IL-22 Protein, Human, Recombinant (hIgG2 hFc)

Cat.No: TMPJ-00061

Species: Human

Expression System: HEK293 Cells

IL-22 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00661

Species: Cynomolgus

Expression System: HEK293 Cells

IL-22 Protein, Human, Recombinant (hIgG4 hFc)

Cat.No: TMPJ-00062

Species: Human

Expression System: HEK293 Cells

IL-22 Protein, Human, Recombinant (His)

Cat.No: TMPY-04973

Species: Human

Expression System: P. pastoris (Yeast)

IL-22RA2 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00119

Species: Human

Expression System: HEK293 Cells

IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01194

Species: Mouse

Expression System: E. coli

IL-22 Protein, Mouse, Recombinant (E. coli)

Cat.No: TMPJ-01339

Species: Mouse

Expression System: E. coli

IL-22BP Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-01324

Species: Human

Expression System: HEK293 Cells

IL-22BP Protein, Human, Recombinant (His)

Cat.No: TMPY-01220

Species: Human

Expression System: HEK293 Cells

IL-22BP Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04900

Species: Human

Expression System: HEK293 Cells

IL-28B Protein, Human, Recombinant

Cat.No: TMPJ-00076

Species: Human

Expression System: HEK293 Cells

IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)

Cat.No: TMPK-00512

Species: Cynomolgus

Expression System: HEK293 Cells

IL-22RA1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-01071

Species: Mouse

Expression System: HEK293 Cells

IL-22RA1 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-01105

Species: Human

Expression System: HEK293 Cells

IL-20RB Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00194

Species: Human

Expression System: HEK293 Cells

IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated

Cat.No: TMPK-00405

Species: Human

Expression System: HEK293 Cells

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